STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
aldh4a1Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial; Irreversible conversion of delta-1-pyrroline-5-carboxylate (P5C), derived either from proline or ornithine, to glutamate. This is a necessary step in the pathway interconnecting the urea and tricarboxylic acid cycles (By similarity); Belongs to the aldehyde dehydrogenase family. (556 aa)    
Predicted Functional Partners:
aldh18a1
Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family.
  
 
 0.990
prodha
Proline dehydrogenase; Converts proline to delta-1-pyrroline-5-carboxylate.
  
 0.982
prodhb
Proline dehydrogenase; Converts proline to delta-1-pyrroline-5-carboxylate.
  
 0.982
zgc:92040
Proline dehydrogenase; Converts proline to delta-1-pyrroline-5-carboxylate.
  
 0.982
oat
Ornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
  
 0.976
pycr1b
Pyrroline-5-carboxylate reductase; Belongs to the pyrroline-5-carboxylate reductase family.
   
 0.973
glud1a
Glutamate dehydrogenase 1a; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
  
 0.957
glud1b
Glutamate dehydrogenase 1b; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
  
 0.957
got2a
Aspartate aminotransferase.
   
 0.956
got1l1
Glutamic-oxaloacetic transaminase 1-like 1.
   
 0.953
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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