Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
pkdccbProtein kinase domain-containing, cytoplasmic b. (481 aa)    
Predicted Functional Partners:
kcng3
Potassium voltage-gated channel, subfamily G, member 3; Belongs to the potassium channel family.
      
 0.778
ccdc36
Coiled-coil domain-containing 36.
      
 0.743
xpc
Xeroderma pigmentosum, complementation group C.
      
 0.733
kbtbd12
Kelch repeat and BTB domain-containing protein 12.
    
 
 0.726
rrp36
Ribosomal RNA-processing 36.
   
  
 0.703
ift140
Intraflagellar transport 140 homolog (Chlamydomonas).
      
 0.687
skilb
SKI-like proto-oncogene b.
   
 0.684
trappc6b
Trafficking protein particle complex subunit 6b; Component of a transport protein particle (TRAPP) complex that may function in specific stages of inter-organelle traffic. Specifically involved in the early development of neural circuitry, likely by controlling the frequency and amplitude of intracellular calcium transients implicated in the regulation of neuron differentiation and survival.
      
 0.672
tmem204
Transmembrane protein 204.
      
 0.660
klc4
Kinesin light chain 4.
    
 0.654
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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