Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
PIGGSi:ch73-49o8.1. (972 aa)    
Predicted Functional Partners:
pigf
Phosphatidylinositol glycan anchor biosynthesis, class F.
    
 0.999
pigk
GPI-anchor transamidase; Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein. Belongs to the peptidase C13 family.
    
 0.997
pigt
Phosphatidylinositol glycan anchor biosynthesis, class T.
    
 0.994
pigo
Phosphatidylinositol glycan anchor biosynthesis, class O.
   
0.989
gpaa1
Glycosylphosphatidylinositol anchor attachment 1.
   
 0.985
pigu
Phosphatidylinositol glycan anchor biosynthesis, class U.
   
 0.968
pigs
Phosphatidylinositol glycan anchor biosynthesis, class S.
   
 0.965
pigl
Phosphatidylinositol glycan anchor biosynthesis, class L.
      
 0.958
pigc
Phosphatidylinositol glycan anchor biosynthesis, class C.
      
 0.949
pigh
Phosphatidylinositol glycan anchor biosynthesis, class H.
    
 
 0.928
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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