STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
wnt6aProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (374 aa)    
Predicted Functional Partners:
vrtn
Vertnin; Belongs to the vertnin family.
      
 0.832
lrp6
Low density lipoprotein receptor-related protein 6.
    
 0.757
porcn
Porcupine O-acyltransferase; Belongs to the membrane-bound acyltransferase family.
    
 0.749
porcnl
Porcupine O-acyltransferase-like; Belongs to the membrane-bound acyltransferase family.
    
 0.749
tpbga
Trophoblast glycoprotein a.
      
 0.744
lrp5
Low density lipoprotein receptor-related protein 5.
    
 0.734
fzd9b
Frizzled class receptor 9b; Belongs to the G-protein coupled receptor Fz/Smo family.
    
 0.711
fzd5
Frizzled class receptor 5; Belongs to the G-protein coupled receptor Fz/Smo family.
    
 0.711
fzd7b
Frizzled class receptor 7b; Belongs to the G-protein coupled receptor Fz/Smo family.
    
 0.711
sfrp1a
Secreted frizzled-related protein 1a.
    
 0.711
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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