Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
fabp10aFatty acid-binding protein 10-A, liver basic; Binds hydrophobic ligands, such as cholate, in the cytoplasm. May be involved in intracellular lipid transport (By similarity). Binds one cholate per subunit. (126 aa)    
Predicted Functional Partners:
ela3l
Elastase 3-like; Belongs to the peptidase S1 family.
   
  
 0.944
gc
GC vitamin D-binding protein.
   
  
 0.924
fabp2
Fatty acid-binding protein 2, intestinal; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
      
 0.900
bhmt
Betaine--homocysteine S-methyltransferase 1; Involved in the regulation of homocysteine metabolism. Converts betaine and homocysteine to dimethylglycine and methionine, respectively. This reaction is also required for the irreversible oxidation of choline (By similarity).
      
 0.799
foxa3
Forkhead box A3.
      
 0.780
hhex
Hematopoietically-expressed homeobox protein hhex; Recognizes the DNA sequence 5'-ATTAA-3' (By similarity). Transcriptional repressor. Regulates the differentiation of both endothelial and blood cells. Plays a role in embryonic dorsoventral patterning by regulating bmp expression. May establish anterior identity. Functions in the embryo to regulate liver development. Functions extraembryonically to generate organ chirality.
   
  
 0.773
myl7
Myosin, light polypeptide 7, regulatory.
      
 0.738
prox1a
Prospero homeobox 1a.
      
 0.711
prss1
Serine protease 1; Belongs to the peptidase S1 family.
   
  
 0.685
hsp70l
Novel protein similar to heat shock cognate 70-kd protein; Belongs to the heat shock protein 70 family.
      
 0.682
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
Server load: low (12%) [HD]