STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
skilaSKI-like proto-oncogene a. (623 aa)    
Predicted Functional Partners:
skia
V-ski avian sarcoma viral oncogene homolog a.
    
  0.992
smad4a
Mothers against decapentaplegic homolog.
    
 0.956
gb:cr929477
SMAD family member 4.
    
 0.956
hdac1
Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.
   
 0.953
skilb
SKI-like proto-oncogene b.
     
  0.948
ncor1
Nuclear receptor corepressor 1.
   
 0.946
sin3ab
SIN3 transcription regulator family member Ab.
   
 0.937
skib
V-ski avian sarcoma viral oncogene homolog b.
     
  0.934
Q1L8R8_DANRE
Mothers against decapentaplegic homolog.
    
 0.921
E7FFZ5_DANRE
Mothers against decapentaplegic homolog.
    
 0.921
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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