| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| LOC100334711 | rbp1.2 | ENSDARP00000022566 | ENSDARP00000056576 | Cyclic nucleotide-gated channel subunit alpha 3b. | Retinol-binding protein 1, cellular, tandem duplicate 2; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. | 0.690 |
| efs | rai14 | ENSDARP00000134894 | ENSDARP00000058484 | Embryonal Fyn-associated substrate. | Retinoic acid-induced 14. | 0.848 |
| efs | rbp1.2 | ENSDARP00000134894 | ENSDARP00000056576 | Embryonal Fyn-associated substrate. | Retinol-binding protein 1, cellular, tandem duplicate 2; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. | 0.838 |
| naprt | nt5e | ENSDARP00000035128 | ENSDARP00000095510 | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Helps prevent cellular oxidative stress via its role in NAD biosynthesis; Belongs to the NAPRTase family. | 5'-nucleotidase, ecto (CD73); Belongs to the 5'-nucleotidase family. | 0.961 |
| naprt | rbp1.2 | ENSDARP00000035128 | ENSDARP00000056576 | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Helps prevent cellular oxidative stress via its role in NAD biosynthesis; Belongs to the NAPRTase family. | Retinol-binding protein 1, cellular, tandem duplicate 2; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. | 0.639 |
| naprt | sirt1 | ENSDARP00000035128 | ENSDARP00000088981 | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Helps prevent cellular oxidative stress via its role in NAD biosynthesis; Belongs to the NAPRTase family. | Sirtuin 1. | 0.674 |
| naprt | sirt2 | ENSDARP00000035128 | ENSDARP00000003412 | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Helps prevent cellular oxidative stress via its role in NAD biosynthesis; Belongs to the NAPRTase family. | NAD-dependent protein deacetylase sirtuin-2; NAD-dependent protein deacetylase, which deacetylates internal lysines on histone and alpha-tubulin as well as many other proteins such as key transcription factors (By similarity). Participates in the modulation of multiple and diverse biological processes such as cell cycle control, genomic integrity, microtubule dynamics, cell differentiation, metabolic networks, and autophagy. Plays a major role in the control of cell cycle progression and genomic stability. Deacetylates histone H4 at 'Lys-16' (H4K16ac) at the VEGFA promoter. Thereby con [...] | 0.524 |
| naprt | sirt5 | ENSDARP00000035128 | ENSDARP00000040792 | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Helps prevent cellular oxidative stress via its role in NAD biosynthesis; Belongs to the NAPRTase family. | NAD-dependent protein deacylase sirtuin-5, mitochondrial; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo. | 0.666 |
| nt5e | naprt | ENSDARP00000095510 | ENSDARP00000035128 | 5'-nucleotidase, ecto (CD73); Belongs to the 5'-nucleotidase family. | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Helps prevent cellular oxidative stress via its role in NAD biosynthesis; Belongs to the NAPRTase family. | 0.961 |
| nt5e | rbp1.2 | ENSDARP00000095510 | ENSDARP00000056576 | 5'-nucleotidase, ecto (CD73); Belongs to the 5'-nucleotidase family. | Retinol-binding protein 1, cellular, tandem duplicate 2; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. | 0.635 |
| rai14 | efs | ENSDARP00000058484 | ENSDARP00000134894 | Retinoic acid-induced 14. | Embryonal Fyn-associated substrate. | 0.848 |
| rai14 | rbp1.2 | ENSDARP00000058484 | ENSDARP00000056576 | Retinoic acid-induced 14. | Retinol-binding protein 1, cellular, tandem duplicate 2; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. | 0.737 |
| rbp1.2 | LOC100334711 | ENSDARP00000056576 | ENSDARP00000022566 | Retinol-binding protein 1, cellular, tandem duplicate 2; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. | Cyclic nucleotide-gated channel subunit alpha 3b. | 0.690 |
| rbp1.2 | efs | ENSDARP00000056576 | ENSDARP00000134894 | Retinol-binding protein 1, cellular, tandem duplicate 2; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. | Embryonal Fyn-associated substrate. | 0.838 |
| rbp1.2 | naprt | ENSDARP00000056576 | ENSDARP00000035128 | Retinol-binding protein 1, cellular, tandem duplicate 2; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Helps prevent cellular oxidative stress via its role in NAD biosynthesis; Belongs to the NAPRTase family. | 0.639 |
| rbp1.2 | nt5e | ENSDARP00000056576 | ENSDARP00000095510 | Retinol-binding protein 1, cellular, tandem duplicate 2; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. | 5'-nucleotidase, ecto (CD73); Belongs to the 5'-nucleotidase family. | 0.635 |
| rbp1.2 | rai14 | ENSDARP00000056576 | ENSDARP00000058484 | Retinol-binding protein 1, cellular, tandem duplicate 2; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. | Retinoic acid-induced 14. | 0.737 |
| rbp1.2 | rgra | ENSDARP00000056576 | ENSDARP00000071634 | Retinol-binding protein 1, cellular, tandem duplicate 2; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. | Retinal pigment epithelium retinal G protein receptor-1. | 0.676 |
| rbp1.2 | sirt1 | ENSDARP00000056576 | ENSDARP00000088981 | Retinol-binding protein 1, cellular, tandem duplicate 2; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. | Sirtuin 1. | 0.668 |
| rbp1.2 | sirt2 | ENSDARP00000056576 | ENSDARP00000003412 | Retinol-binding protein 1, cellular, tandem duplicate 2; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. | NAD-dependent protein deacetylase sirtuin-2; NAD-dependent protein deacetylase, which deacetylates internal lysines on histone and alpha-tubulin as well as many other proteins such as key transcription factors (By similarity). Participates in the modulation of multiple and diverse biological processes such as cell cycle control, genomic integrity, microtubule dynamics, cell differentiation, metabolic networks, and autophagy. Plays a major role in the control of cell cycle progression and genomic stability. Deacetylates histone H4 at 'Lys-16' (H4K16ac) at the VEGFA promoter. Thereby con [...] | 0.668 |