STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ubtfUpstream-binding transcription factor. (735 aa)    
Predicted Functional Partners:
dcaf5
Ddb1 and cul4-associated factor 5.
      
 0.724
polr1a
DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.708
las1l
LAS1-like ribosome biogenesis factor.
      
 0.695
taf1b
TATA box-binding protein-associated factor RNA polymerase I subunit B; Component of RNA polymerase I core factor complex that acts as a GTF2B/TFIIB-like factor and plays a key role in multiple steps during transcription initiation such as pre-initiation complex (PIC) assembly and postpolymerase recruitment events in polymerase I (Pol I) transcription. Binds rDNA promoters and plays a role in Pol I recruitment (By similarity).
   
 
 0.675
stk38a
Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.
    
 
 0.633
hnrnpaba
Heterogeneous nuclear ribonucleoprotein A/Ba.
   
 
 0.611
sirt7
Sirtuin 7.
    
 
 0.597
ncl
Nucleolin.
   
 
 0.577
ap3d1
Adaptor-related protein complex 3 subunit delta 1.
   
  
 0.558
mier1a
Mesoderm induction early response 1a, transcriptional regulator.
    
 
 0.551
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.