STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tmem53Transmembrane protein 53. (281 aa)    
Predicted Functional Partners:
ENSDARP00000131983
Si:dkey-31f5.11.
   
  
 0.958
prrt4
Proline-rich transmembrane protein 4.
   
  
 0.924
lrrc4.1
Leucine-rich repeat-containing 4.1.
      
 0.845
rbm28
RNA-binding motif protein 28.
      
 0.837
sh3yl1
SH3 and SYLF domain-containing 1.
      
 0.808
hsd11b1lb
Hydroxysteroid (11-beta) dehydrogenase 1-like b.
      
 0.720
LOC565819
Si:ch211-13k12.2.
      
 0.718
acbd6
Acyl-CoA-binding domain-containing protein 6; Binds long-chain acyl-coenzyme A molecules with a strong preference for unsaturated C18:1-CoA. Does not bind fatty acids (By similarity).
      
 0.628
tmem223
Transmembrane protein 223.
   
  
 0.617
micos13
MICOS complex subunit MIC13; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. Constituent of mature MICOS complex, it is required for the formation of cristae junction (CJ) and maintenance of cristae morphology. Required for the incorporation of MIC10 into the MICOS complex.
   
  
 0.574
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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