STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
e2f5E2F transcription factor 5 (363 aa)    
Predicted Functional Partners:
rbl1
Retinoblastoma-like 1 (p107)
   
 0.998
rbl2
Retinoblastoma-like 2 (p130)
   
 0.994
tfdp1a
Transcription factor Dp-1, a
   
 0.988
tfdp2
Transcription factor Dp-2
   
 0.987
lin54
Protein lin-54 homolog; Component of the DREAM complex, a multiprotein complex that can both act as a transcription activator or repressor depending on the context. Specifically recognizes the consensus motif 5'-TTYRAA-3' in target DNA; Belongs to the lin-54 family
   
 0.985
lin9
Lin-9 homolog (C. elegans); Belongs to the lin-9 family
   
 0.984
ccna2
Ccna2 protein; Cyclin A2; Belongs to the cyclin family
   
 0.977
lin52
Lin-52 homolog (C. elegans)
   
 0.976
cdk2
Cyclin-dependent kinase 2; Belongs to the protein kinase superfamily
   
 0.971
lin37
Lin-37 DREAM MuvB core complex component; Lin-37 homolog (C. elegans)
   
 0.971
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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