STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
e2f5E2F transcription factor 5. (363 aa)    
Predicted Functional Partners:
rb1
Retinoblastoma 1.
   
 0.987
rbl2
Retinoblastoma-like 2 (p130).
   
 0.982
rbl1
Retinoblastoma-like 1 (p107).
   
 0.982
tfdp2
Transcription factor.
  
 0.960
e2f4
E2F transcription factor 4.
  
  
0.953
tfdp1a
Transcription factor.
   
 0.951
mcidas
Uncharacterized protein.
      
 0.900
lin37
Lin-37 DREAM MuvB core complex component.
    
 0.887
lin9
Protein lin-9 homolog; Belongs to the lin-9 family.
   
 0.866
lin54
Protein lin-54 homolog; Component of the DREAM complex, a multiprotein complex that can both act as a transcription activator or repressor depending on the context. Specifically recognizes the consensus motif 5'-TTYRAA-3' in target DNA; Belongs to the lin-54 family.
   
 0.852
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.