Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
pdcd7Programmed cell death 7. (508 aa)    
Predicted Functional Partners:
zmat5
Zinc finger matrin-type protein 5.
    
 0.994
snrnp25
Small nuclear ribonucleoprotein 25.
   
 0.980
snrnp35
U11/U12 small nuclear ribonucleoprotein 35 kDa protein.
    
 0.978
zcrb1
Zinc finger CCHC-type and RNA-binding motif-containing protein 1.
    
 0.973
snrpg
Small nuclear ribonucleoprotein G.
    
  0.973
zrsr2
Zinc finger (CCCH type), RNA-binding motif and serine/arginine-rich 2.
    
   0.959
snrpe
Small nuclear ribonucleoprotein E; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing.
   
  0.955
rnpc3
RNA-binding region-containing protein 3; Participates in pre-mRNA U12-dependent splicing, performed by the minor spliceosome which removes U12-type introns. U12-type introns comprise less than 1% of all non-coding sequences.
   
 0.926
sf3b1
Splicing factor 3b, subunit 1.
   
  0.905
sf3b2
Splicing factor 3b, subunit 2.
   
 
  0.901
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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