STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fbxo5F-box only protein 5; During embryonic development, regulates the integrity of the genome and therefore the cell cycle progression by preventing rereplication through an APC-Cdh1-dependent mechanism. (384 aa)    
Predicted Functional Partners:
cdc20
Cell division cycle 20 homolog.
   
 
  0.923
cth1
Putative zinc finger protein.
   
 
  0.914
fbxw11b
F-box and WD repeat domain-containing 11b.
   
 
  0.901
rbx1
Ring-box 1, E3 ubiquitin protein ligase.
   
 
  0.901
skp1
S-phase kinase-associated protein 1A; Belongs to the SKP1 family.
   
 
  0.900
cul1a
Cullin 1a; Belongs to the cullin family.
     
  0.900
cul1b
Cullin 1b; Belongs to the cullin family.
     
  0.900
gins2
DNA replication complex GINS protein PSF2; Belongs to the GINS2/PSF2 family.
   
  
 0.844
rflnb
Refilin B.
      
 0.832
plk1
Serine/threonine-protein kinase PLK.
   
 
  0.811
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.