| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| cwc22 | cwc27 | ENSDARP00000013971 | ENSDARP00000064209 | Pre-mRNA-splicing factor CWC22 homolog; Required for pre-mRNA splicing as component of the spliceosome. Promotes exon-junction complex (EJC) assembly. | Spliceosome-associated protein CWC27 homolog; As part of the spliceosome, plays a role in pre-mRNA splicing. Probable inactive PPIase with no peptidyl-prolyl cis-trans isomerase activity. | 0.992 |
| cwc22 | mfap1 | ENSDARP00000013971 | ENSDARP00000017863 | Pre-mRNA-splicing factor CWC22 homolog; Required for pre-mRNA splicing as component of the spliceosome. Promotes exon-junction complex (EJC) assembly. | Microfibril-associated protein 1. | 0.401 |
| cwc22 | plrg1 | ENSDARP00000013971 | ENSDARP00000054234 | Pre-mRNA-splicing factor CWC22 homolog; Required for pre-mRNA splicing as component of the spliceosome. Promotes exon-junction complex (EJC) assembly. | Pleiotropic regulator 1. | 0.914 |
| cwc22 | prpf31 | ENSDARP00000013971 | ENSDARP00000120708 | Pre-mRNA-splicing factor CWC22 homolog; Required for pre-mRNA splicing as component of the spliceosome. Promotes exon-junction complex (EJC) assembly. | U4/U6 small nuclear ribonucleoprotein Prp31; Involved in pre-mRNA splicing as component of the spliceosome. Required for the assembly of the U4/U5/U6 tri-snRNP complex, one of the building blocks of the spliceosome. | 0.932 |
| cwc22 | prpf38a | ENSDARP00000013971 | ENSDARP00000057289 | Pre-mRNA-splicing factor CWC22 homolog; Required for pre-mRNA splicing as component of the spliceosome. Promotes exon-junction complex (EJC) assembly. | Pre-mRNA-splicing factor 38A; Involved in pre-mRNA splicing as a component of the spliceosome. | 0.938 |
| cwc22 | sf3b3 | ENSDARP00000013971 | ENSDARP00000134109 | Pre-mRNA-splicing factor CWC22 homolog; Required for pre-mRNA splicing as component of the spliceosome. Promotes exon-junction complex (EJC) assembly. | Splicing factor 3B subunit 3; Involved in pre-mRNA splicing as a component of the splicing factor SF3B complex, a constituent of the spliceosome. SF3B complex is required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA. May also be involved in the assembly of the 'E' complex. Belongs also to the minor U12- dependent spliceosome, which is involved in the splicing of rare class of nuclear pre-mR [...] | 0.983 |
| cwc22 | smu1a | ENSDARP00000013971 | ENSDARP00000089117 | Pre-mRNA-splicing factor CWC22 homolog; Required for pre-mRNA splicing as component of the spliceosome. Promotes exon-junction complex (EJC) assembly. | WD40 repeat-containing protein SMU1; Involved in pre-mRNA splicing as a component of the spliceosome (By similarity). Required for normal accumulation of ik (By similarity). Required for normal mitotic spindle assembly and normal progress through mitosis (By similarity). Belongs to the WD repeat SMU1 family. | 0.900 |
| cwc22 | snrpe | ENSDARP00000013971 | ENSDARP00000050295 | Pre-mRNA-splicing factor CWC22 homolog; Required for pre-mRNA splicing as component of the spliceosome. Promotes exon-junction complex (EJC) assembly. | Small nuclear ribonucleoprotein E; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. | 0.987 |
| cwc27 | cwc22 | ENSDARP00000064209 | ENSDARP00000013971 | Spliceosome-associated protein CWC27 homolog; As part of the spliceosome, plays a role in pre-mRNA splicing. Probable inactive PPIase with no peptidyl-prolyl cis-trans isomerase activity. | Pre-mRNA-splicing factor CWC22 homolog; Required for pre-mRNA splicing as component of the spliceosome. Promotes exon-junction complex (EJC) assembly. | 0.992 |
| cwc27 | plrg1 | ENSDARP00000064209 | ENSDARP00000054234 | Spliceosome-associated protein CWC27 homolog; As part of the spliceosome, plays a role in pre-mRNA splicing. Probable inactive PPIase with no peptidyl-prolyl cis-trans isomerase activity. | Pleiotropic regulator 1. | 0.795 |
| cwc27 | prpf31 | ENSDARP00000064209 | ENSDARP00000120708 | Spliceosome-associated protein CWC27 homolog; As part of the spliceosome, plays a role in pre-mRNA splicing. Probable inactive PPIase with no peptidyl-prolyl cis-trans isomerase activity. | U4/U6 small nuclear ribonucleoprotein Prp31; Involved in pre-mRNA splicing as component of the spliceosome. Required for the assembly of the U4/U5/U6 tri-snRNP complex, one of the building blocks of the spliceosome. | 0.956 |
| cwc27 | prpf38a | ENSDARP00000064209 | ENSDARP00000057289 | Spliceosome-associated protein CWC27 homolog; As part of the spliceosome, plays a role in pre-mRNA splicing. Probable inactive PPIase with no peptidyl-prolyl cis-trans isomerase activity. | Pre-mRNA-splicing factor 38A; Involved in pre-mRNA splicing as a component of the spliceosome. | 0.927 |
| cwc27 | sf3b3 | ENSDARP00000064209 | ENSDARP00000134109 | Spliceosome-associated protein CWC27 homolog; As part of the spliceosome, plays a role in pre-mRNA splicing. Probable inactive PPIase with no peptidyl-prolyl cis-trans isomerase activity. | Splicing factor 3B subunit 3; Involved in pre-mRNA splicing as a component of the splicing factor SF3B complex, a constituent of the spliceosome. SF3B complex is required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA. May also be involved in the assembly of the 'E' complex. Belongs also to the minor U12- dependent spliceosome, which is involved in the splicing of rare class of nuclear pre-mR [...] | 0.981 |
| cwc27 | smu1a | ENSDARP00000064209 | ENSDARP00000089117 | Spliceosome-associated protein CWC27 homolog; As part of the spliceosome, plays a role in pre-mRNA splicing. Probable inactive PPIase with no peptidyl-prolyl cis-trans isomerase activity. | WD40 repeat-containing protein SMU1; Involved in pre-mRNA splicing as a component of the spliceosome (By similarity). Required for normal accumulation of ik (By similarity). Required for normal mitotic spindle assembly and normal progress through mitosis (By similarity). Belongs to the WD repeat SMU1 family. | 0.909 |
| cwc27 | snrpe | ENSDARP00000064209 | ENSDARP00000050295 | Spliceosome-associated protein CWC27 homolog; As part of the spliceosome, plays a role in pre-mRNA splicing. Probable inactive PPIase with no peptidyl-prolyl cis-trans isomerase activity. | Small nuclear ribonucleoprotein E; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. | 0.982 |
| mfap1 | cwc22 | ENSDARP00000017863 | ENSDARP00000013971 | Microfibril-associated protein 1. | Pre-mRNA-splicing factor CWC22 homolog; Required for pre-mRNA splicing as component of the spliceosome. Promotes exon-junction complex (EJC) assembly. | 0.401 |
| mfap1 | plrg1 | ENSDARP00000017863 | ENSDARP00000054234 | Microfibril-associated protein 1. | Pleiotropic regulator 1. | 0.770 |
| mfap1 | prpf31 | ENSDARP00000017863 | ENSDARP00000120708 | Microfibril-associated protein 1. | U4/U6 small nuclear ribonucleoprotein Prp31; Involved in pre-mRNA splicing as component of the spliceosome. Required for the assembly of the U4/U5/U6 tri-snRNP complex, one of the building blocks of the spliceosome. | 0.926 |
| mfap1 | prpf38a | ENSDARP00000017863 | ENSDARP00000057289 | Microfibril-associated protein 1. | Pre-mRNA-splicing factor 38A; Involved in pre-mRNA splicing as a component of the spliceosome. | 0.990 |
| mfap1 | sf3b3 | ENSDARP00000017863 | ENSDARP00000134109 | Microfibril-associated protein 1. | Splicing factor 3B subunit 3; Involved in pre-mRNA splicing as a component of the splicing factor SF3B complex, a constituent of the spliceosome. SF3B complex is required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA. May also be involved in the assembly of the 'E' complex. Belongs also to the minor U12- dependent spliceosome, which is involved in the splicing of rare class of nuclear pre-mR [...] | 0.907 |
