Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
cep78Centrosomal protein 78. (672 aa)    
Predicted Functional Partners:
ddb1
Damage-specific DNA-binding protein 1.
    
 
 0.940
fgfr1op
Chemokine (C-C motif) receptor 6a.
    
   0.928
ubr5
Ubiquitin protein ligase E3 component n-recognin 5.
    
 
 0.891
ENSDARP00000149604
Uncharacterized protein.
    
 
 0.891
armc2
Armadillo repeat-containing 2.
      
 0.808
tmem82
Transmembrane protein 82.
      
 0.796
cep128
Centrosomal protein 128.
    
 
 0.765
arsg
Arylsulfatase G.
      
 0.747
WDR63
WD repeat domain 63.
    
 
 0.739
cep290
Centrosomal protein of 290 kDa; Involved in early and late steps in cilia formation. May play a role in early ciliogenesis in the disappearance of centriolar satellites and in the transition of primary ciliar vesicles (PCVs) to capped ciliary vesicles (CCVs). In the ciliary transition zone is part of the tectonic-like complex which is required for tissue-specific ciliogenesis and may regulate ciliary membrane composition. Involved in regulation of the BBSome complex integrity and in ciliary targeting of selected BBSome cargos. Required for the correct localization of ciliary and photot [...]
    
 
 0.715
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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