STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
igfbp5bInsulin-like growth factor binding protein 5a (268 aa)    
Predicted Functional Partners:
igf1
Insulin-like growth factor 1
   
 0.995
igf2a
Insulin-like growth factor 2a
   
 0.984
igf2b
Insulin-like growth factor 2b
   
 0.983
igfbp7
Insulin-like growth factor binding protein 7
   
 
 0.956
fn1a
Fibronectin 1a
   
 0.953
IGFALS
Insulin-like growth factor binding protein, acid labile subunit
    
 0.948
pappaa
Pregnancy-associated plasma protein A, pappalysin 1a
   
 0.936
pappab
Pregnancy-associated plasma protein A, pappalysin 1b
   
 0.936
apobb
Apolipoprotein Bb, tandem duplicate 1; Apolipoprotein Bb
   
 
 0.931
pappa2
Pappalysin 2
   
 0.930
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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