Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
pmepa1Prostate transmembrane protein, androgen-induced 1. (193 aa)    
Predicted Functional Partners:
fbl
Fibrillarin.
   
 
 0.723
msl2b
MSL complex subunit 2b.
      
 0.667
tmem150c
Transmembrane protein 150C.
      
 0.662
rps2
Ribosomal protein S2; Belongs to the universal ribosomal protein uS5 family.
   
 
 0.631
gar1
H/ACA ribonucleoprotein complex subunit 1; Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ('psi') residues may serve to stabilize the conformation of rRNAs (By similarity).
   
 
 0.620
noc2l
NOC2-like nucleolar-associated transcriptional repressor.
   
   0.598
serf2
Small EDRK-rich factor 2.
      
 0.595
msl2a
MSL complex subunit 2a.
      
 0.594
rrp12
Ribosomal RNA-processing 12 homolog.
   
 
 0.591
rpf2
Ribosome production factor 2 homolog.
   
  
 0.575
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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