Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
cep68Centrosomal protein 68. (650 aa)    
Predicted Functional Partners:
tmem116
Transmembrane protein 116.
      
 0.839
ttbk2b
Tau tubulin kinase 2b.
   
  
 0.672
wipf1b
WAS/WASL-interacting protein family, member 1b.
      
 0.642
cops9
COP9 signalosome complex subunit 9; Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF- type E3 ligase complexes, leading to decrease the Ubl ligase activity. May play a role in cell proliferation.
      
 0.611
cand2
Cullin-associated and neddylation-dissociated 2 (putative).
      
 0.610
ldah
Lipid droplet-associated hydrolase.
      
 0.609
ttbk1b
Tau tubulin kinase 1b.
      
 0.596
ttbk1a
Tau tubulin kinase 1a.
      
 0.594
lrrc45
Leucine-rich repeat-containing 45.
      
 0.594
SFMBT1
Scm like with four mbt domains 1.
      
 0.594
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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