Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
dmrta2Doublesex- and mab-3-related transcription factor A2; May be involved in sexual development; Belongs to the DMRT family. (440 aa)    
Predicted Functional Partners:
armh1
Armadillo-like helical domain-containing 1.
      
 0.732
foxl2a
Forkhead box L2-1.
   
 
 0.614
amh
Anti-Mullerian hormone.
      
 0.594
tex9
Testis-expressed 9.
      
 0.568
fbxl6
F-box and leucine-rich repeat protein 6.
      
 0.559
abhd17ab
Abhydrolase domain-containing 17Ab.
      
 0.559
emx3
Empty spiracles homeobox 3.
   
 
 0.551
maats1
MYCBP-associated, testis-expressed 1.
      
 0.523
emx1
Homeobox protein EMX1; May function in combinations with OTX1/2 to specify cell fates in the developing central nervous system; Belongs to the EMX homeobox family.
   
 
 0.522
hmgcll1
3-hydroxy-3-methylglutaryl-CoA lyase, cytoplasmic; Non-mitochondrial 3-hydroxymethyl-3-methylglutaryl-CoA lyase that catalyzes a cation-dependent cleavage of (S)-3-hydroxy-3- methylglutaryl-CoA into acetyl-CoA and acetoacetate, a key step in ketogenesis, the products of which support energy production in nonhepatic animal tissues.
      
 0.501
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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