Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
tspan15Tetraspanin. (296 aa)    
Predicted Functional Partners:
adam10a
ADAM metallopeptidase domain 10a.
    
 
 0.751
adam10b
ADAM metallopeptidase domain 10b.
    
 
 0.703
tspan2b
Tetraspanin.
    
 
 0.696
tspan13b
Tetraspanin 13b; Belongs to the tetraspanin (TM4SF) family.
      
 0.689
cd9a
Tetraspanin.
    
 
0.577
tspan31
Tetraspanin-31.
      
 0.559
napaa
N-ethylmaleimide-sensitive factor attachment protein, alpha a.
      
 0.501
tspan1
Tetraspanin.
      
 0.495
thbs3a
Thrombospondin-3a; Adhesive glycoprotein that mediates cell-to-cell and cell-to- matrix interactions. Can bind to fibrinogen, fibronectin, laminin and type V collagen (By similarity).
      
 0.490
pmvk
Phosphomevalonate kinase.
      
 0.490
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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