Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
qsox1Sulfhydryl oxidase. (778 aa)    
Predicted Functional Partners:
qpctla
Glutaminyl-peptide cyclotransferase-like a.
   
  
 0.737
qpctlb
Glutaminyl-peptide cyclotransferase-like b.
   
  
 0.702
cxcl18a.1
Chemokine (C-X-C motif) ligand 18a, duplicate 1.
      
 0.569
LOC569071
Protein tyrosine phosphatase receptor type H.
      
 0.561
ptprh
Protein tyrosine phosphatase receptor type H.
      
 0.561
fam13a
Family with sequence similarity 13 member A.
      
 0.557
pdia6
Protein disulfide isomerase family A, member 6; Belongs to the protein disulfide isomerase family.
   
 
 0.551
txndc5
Thioredoxin domain-containing 5; Belongs to the protein disulfide isomerase family.
     
 0.550
ero1a
ERO1-like protein alpha; Oxidoreductase involved in disulfide bond formation in the endoplasmic reticulum. Efficiently reoxidizes P4HB/PDI, the enzyme catalyzing protein disulfide formation, in order to allow P4HB to sustain additional rounds of disulfide formation. Following P4HB reoxidation, passes its electrons to molecular oxygen via FAD, leading to the production of reactive oxygen species (ROS) in the cell. Required for the folding of immunoglobulins (By similarity). Belongs to the EROs family.
     
 0.540
ero1b
Endoplasmic reticulum oxidoreductase beta.
     
 0.540
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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