Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
nrgnaNeurogranin (protein kinase C substrate, RC3) a. (60 aa)    
Predicted Functional Partners:
brsk2a
Protein kinase domain-containing protein.
      
 0.739
brsk2b
BR serine/threonine kinase 2b.
      
 0.738
tiprl
TIP41, TOR-signaling pathway regulator-like (S. cerevisiae).
      
 0.670
msi2b
Musashi homolog 2b (Drosophila).
      
 0.597
ube2ka
Ubiquitin-conjugating enzyme E2Ka (UBC1 homolog, yeast); Belongs to the ubiquitin-conjugating enzyme family.
      
 0.594
tbcelb
Tubulin folding cofactor E-like b.
      
 0.594
cpne2
Copine II.
   
  
 0.593
ywhag2
3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide 2; Belongs to the 14-3-3 family.
      
 0.576
kcnj11l-2
Potassium inwardly rectifying channel subfamily J member 11,-like.
      
 0.571
ppp1r14ba
Protein phosphatase 1, regulatory (inhibitor) subunit 14Ba.
      
 0.567
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
Server load: low (16%) [HD]