Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
zgc:123321Zgc:123321. (247 aa)    
Predicted Functional Partners:
yif1b
Protein YIF1B.
   
 
 0.762
yif1a
Protein YIF1A; Possible role in transport between endoplasmic reticulum and Golgi; Belongs to the YIF1 family.
   
 
 0.762
yipf1
Protein YIPF.
   
 
 0.728
yipf2
Protein YIPF.
   
 
 0.728
ier3ip1
Immediate early response 3-interacting protein 1; May be involved in protein transport between endoplasmic reticulum and Golgi apparatus; Belongs to the YOS1 family.
   
 
 0.720
rabac1
PRA1 family protein.
   
 
 0.718
derl1
Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.
   
 
 0.701
yipf3
Protein YIPF3; Involved in the maintenance of the Golgi structure. May play a role in hematopoiesis (By similarity); Belongs to the YIP1 family.
   
 
 0.678
tmed10
Transmembrane emp24-like trafficking protein 10 (Yeast).
   
 
 0.621
sec13
SEC13 homolog, nuclear pore and COPII coat complex component; Belongs to the WD repeat SEC13 family.
   
 
 0.595
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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