STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ldlrap1bLow density lipoprotein receptor adaptor protein 1b. (304 aa)    
Predicted Functional Partners:
ldlra
Low density lipoprotein receptor a.
   
 0.951
lrp2a
Low density lipoprotein receptor-related protein 2a.
    
 0.947
ap2b1
AP complex subunit beta.
    
 0.945
ENSDARP00000146183
Si:ch211-204c21.1.
   
 
 0.923
ap2m1a
AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...]
    
 0.918
si:dkey-71h2.2
Si:dkey-71h2.2.
  
  
 
0.902
ldlrap1a
Low density lipoprotein receptor adaptor protein 1a.
  
  
 
0.901
LOC103910581
Huntingtin-interacting protein 1-related a.
      
 0.839
hip1rb
Huntingtin-interacting protein 1-related b.
   
  
 0.839
apoba
Apolipoprotein Ba.
     
 0.818
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.