Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
bbs5Bardet-Biedl syndrome 5 protein homolog; Required for ciliogenesis; Belongs to the BBS5 family. (342 aa)    
Predicted Functional Partners:
bbs2
Bardet-Biedl syndrome 2 protein homolog; Required for ciliogenesis.
    
 0.999
bbs7
Bardet-Biedl syndrome 7 protein homolog; The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function.
   
 0.999
bbs1
Bardet-Biedl syndrome 1.
  
 
 0.999
bbs9
Bardet-Biedl syndrome 9.
   
 0.998
ttc8
Tetratricopeptide repeat domain 8.
  
 0.994
bbip1
BBSome-interacting protein 1; Required for primary cilia assembly; Belongs to the BBIP10 family.
   
 0.989
bbs4
Bardet-Biedl syndrome 4.
    
 0.969
lztfl1
Leucine zipper transcription factor-like 1.
   
 0.962
bbs10
Bardet-Biedl syndrome 10.
    
 
 0.956
bbs12
Bardet-Biedl syndrome 12.
      
 0.955
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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