Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
znf800bZinc finger protein 800b. (504 aa)    
Predicted Functional Partners:
atf5b
Activating transcription factor 5b.
    
 
 0.683
hoxc1a
Homeobox protein Hox-C1a; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
    
 
 0.664
creb3l3l
cAMP-responsive element-binding protein 3-like 3 like.
      
 0.662
creb3l3a
Processed cyclic AMP-responsive element-binding protein 3-like protein 3-B; Transcriptional activator. Binds the cAMP response element (CRE). Activates transcription through box-B element and CRE. Seems to function synergistically with atf6 (By similarity).
      
 0.662
tefa
TEF transcription factor, PAR bZIP family member a.
    
 
 0.592
nfe2l1a
Nuclear factor, erythroid 2-like 1a.
      
 0.589
unc45b
Protein unc-45 homolog B; Acts as a co-chaperone for HSP90 and is required for proper folding of the myosin motor domain (By similarity). Plays a role in sarcomere formation during muscle cell development. Required for myoseptal integrity, myofiber attachment, motility and craniofacial development. Is necessary for normal early lens development.
    
 
 0.559
srfb
Serum response factor b.
    
 0.535
rrp8
Ribosomal RNA-processing protein 8; Probable methyltransferase required to silence rDNA. Belongs to the methyltransferase superfamily. RRP8 family.
    
   0.517
mxtx1
Mix-type homeobox gene 1.
    
 
 0.509
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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