Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
dusp22bDual specificity protein phosphatase 22-B; Activates the Jnk signaling pathway. Dephosphorylates and deactivates p38 and stress-activated protein kinase/c-Jun N-terminal kinase (SAPK/JNK) (By similarity). (183 aa)    
Predicted Functional Partners:
fam120b
Family with sequence similarity 120B.
    
 
 0.786
exoc2
Exocyst complex component 2; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. Belongs to the SEC5 family.
      
 0.786
gmds
GDP-mannose 4,6 dehydratase.
      
 0.666
C18H19orf54
UPF0692 protein C19orf54 homolog; Belongs to the UPF0692 family.
      
 0.627
mustn1b
Musculoskeletal, embryonic nuclear protein 1b.
    
 0.627
HUS1B
Checkpoint protein; Belongs to the HUS1 family.
   
  
 0.607
foxf2a
Forkhead box F2a.
    
 0.581
foxf2b
Forkhead box F2b.
    
 0.581
ppp1r42
Protein phosphatase 1 regulatory subunit 42; May regulate phosphatase activity of protein phosphatase 1 (PP1) complexes.
   
 
 0.573
irf4a
Interferon regulatory factor 4a.
 
  
 0.572
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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