Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
rpz4Rapunzel 4. (391 aa)    
Predicted Functional Partners:
cpa4
Carboxypeptidase A4.
      
 0.719
cpa2
Carboxypeptidase A2 (pancreatic).
      
 0.684
LOC101883528
SCP domain-containing protein; Belongs to the CRISP family.
      
 0.595
atp6ap2
ATPase H+-transporting accessory protein 2.
      
 0.594
rgl3a
Ral guanine nucleotide dissociation stimulator-like 3a.
      
 0.561
sc:d189
Sc:d189.
  
     0.486
zgc:172122
Zgc:172122 protein.
  
     0.483
med21
Mediator of RNA polymerase II transcription subunit 21; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
      
 0.469
zgc:113337
Zgc:113337.
  
     0.465
igsf8
Immunoglobulin superfamily, member 8.
  
     0.464
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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