Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ppt1Palmitoyl-protein thioesterase 1 (ceroid-lipofuscinosis, neuronal 1, infantile). (303 aa)    
Predicted Functional Partners:
ppt2
Novel protein similar to verebrate palmitoyl-protein thioesterase 2 (PPT2).
     
0.966
acsbg2
Acyl-CoA synthetase bubblegum family member 2.
   
 
 0.961
acsl5
Acyl-CoA synthetase long chain family member 5.
   
 
 0.959
acsl3b
Acyl-CoA synthetase long chain family member 3b.
   
 
 0.955
acsl3a
Acyl-CoA synthetase long chain family member 3a.
   
 
 0.955
zgc:55621-2
Zgc:66024.
     
 0.955
mecr
Enoyl-[acyl-carrier-protein] reductase, mitochondrial; Catalyzes the NADPH-dependent reduction of trans-2-enoyl thioesters in mitochondrial fatty acid synthesis (fatty acid synthesis type II). Fatty acid chain elongation in mitochondria uses acyl carrier protein (ACP) as an acyl group carrier, but the enzyme accepts both ACP and CoA thioesters as substrates in vitro. Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.
   
 
 0.953
acsl2
Acyl-CoA synthetase long chain family member 2.
   
 
 0.951
acsbg1
Acyl-CoA synthetase bubblegum family member 1.
   
 
 0.951
LOC101884755
PKS_ER domain-containing protein.
   
 
 0.945
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
Server load: low (12%) [HD]