STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gbpGlycogen synthase kinase-binding protein. (149 aa)    
Predicted Functional Partners:
gsk3ba
Glycogen synthase kinase 3 beta, genome duplicate a; Belongs to the protein kinase superfamily.
    
 0.965
gsk3bb
Glycogen synthase kinase 3 beta, genome duplicate b; Belongs to the protein kinase superfamily.
    
 0.965
dvl2
Dishevelled segment polarity protein 2.
    
 0.916
dvl3a
Dishevelled segment polarity protein 3a.
    
 0.916
dvl1b
Dishevelled segment polarity protein 1b.
    
 0.916
dvl1a
Dishevelled segment polarity protein 1a.
    
 0.916
dvl3
Dishevelled segment polarity protein 3b.
    
 0.916
gsk3aa
Glycogen synthase kinase 3 alpha a; Belongs to the protein kinase superfamily.
   
 
 0.672
gsk3ab
Glycogen synthase kinase 3 alpha b; Belongs to the protein kinase superfamily.
    
 
 0.670
axin1
Axin-1; Component of the beta-catenin destruction complex required for regulating ctnnb1 levels through phosphorylation and ubiquitination, and modulating Wnt-signaling. Controls dorsoventral patterning via two opposing effects: down- regulates ctnnb1 to inhibit the Wnt signaling pathway and ventralize embryos, but also dorsalizes embryos by activating a Wnt-independent JNK signaling pathway.
    
 0.578
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.