Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
gbpGlycogen synthase kinase-binding protein. (149 aa)    
Predicted Functional Partners:
gsk3bb
Glycogen synthase kinase 3 beta, genome duplicate b; Belongs to the protein kinase superfamily.
    
 0.995
gsk3ba
Glycogen synthase kinase 3 beta, genome duplicate a; Belongs to the protein kinase superfamily.
    
 0.956
dvl2
Dishevelled segment polarity protein 2.
    
 0.949
gsk3ab
Glycogen synthase kinase 3 alpha b; Belongs to the protein kinase superfamily.
    
 0.896
gsk3aa
Glycogen synthase kinase 3 alpha a; Belongs to the protein kinase superfamily.
    
 0.896
dvl3a
Dishevelled segment polarity protein 3a.
    
 0.890
dvl3
Dishevelled segment polarity protein 3b.
    
 0.890
dvl1b
Dishevelled segment polarity protein 1b.
    
 0.828
dvl1a
Dishevelled segment polarity protein 1a.
    
 0.828
F8W5A4_DANRE
Si:ch73-236e11.2.
    
 0.828
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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