STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
acta1bActin alpha 1, skeletal muscle b. (377 aa)    
Predicted Functional Partners:
actn3b
Actinin alpha 3b.
   
 
 0.998
vclb
Vinculin b.
   
 
 0.998
vcla
Vinculin a.
   
 
 0.998
cfl1
Muscle cofilin 2; Belongs to the actin-binding proteins ADF family.
   
 
 0.997
cfl1l
Cofilin 1 (non-muscle),-like; Belongs to the actin-binding proteins ADF family.
   
 
 0.996
cfl2
Cofilin 2 (Muscle); Belongs to the actin-binding proteins ADF family.
   
 
 0.996
ezrb
Ezrin b.
   
 
 0.991
msna
Moesin a.
   
 
 0.989
tjp1a
Tight junction protein 1a; Belongs to the MAGUK family.
    
 
 0.989
pfn1
Profilin; Belongs to the profilin family.
   
 
 0.988
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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