Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
nek4NIMA-related kinase 4. (849 aa)    
Predicted Functional Partners:
rpgrip1l
RPGRIP1-like.
   
 
 0.783
tmem185
Transmembrane protein 185-like.
      
 0.752
znf800a
Zinc finger protein 800a.
     
 0.743
spata7
Spermatogenesis-associated 7.
   
 
 0.732
cmc2
COX assembly mitochondrial protein 2 homolog; May be involved in cytochrome c oxidase biogenesis. Belongs to the CMC family.
      
 0.721
rpgrip1
RPGR-interacting protein 1.
    
 
 0.699
ttc21b
Tetratricopeptide repeat domain 21B.
    
 
 0.632
zgc:113423
Zgc:113423.
      
 0.622
prkra
Interferon-inducible double-stranded RNA-dependent protein kinase activator A homolog; Activates eif2ak2/pkr in the absence of double-stranded RNA (dsRNA), leading to phosphorylation of eif2s1/efi2-alpha and inhibition of translation and induction of apoptosis. Required for siRNA production by dicer1 and for subsequent siRNA-mediated post- transcriptional gene silencing. Does not seem to be required for processing of pre-miRNA to miRNA by dicer1 (By similarity).
      
 0.609
snrnp70
Small nuclear ribonucleoprotein 70 (U1).
      
 0.604
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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