Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
cdc42lCell division cycle 42,-like. (191 aa)    
Predicted Functional Partners:
pak1
Non-specific serine/threonine protein kinase.
   
 0.981
diaph3
Diaphanous-related formin 3.
   
 0.979
iqgap2
IQ motif-containing GTPase-activating protein 2.
   
 0.976
pak7
P21 protein (Cdc42/Rac)-activated kinase 7.
   
 0.976
iqgap3
IQ motif-containing GTPase-activating protein 3.
   
 0.975
wasb
WASP actin nucleation-promoting factor b.
   
 0.974
pik3cb
Phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta; Belongs to the PI3/PI4-kinase family.
    
 0.974
pik3ca
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.
    
 0.974
wasa
WASP actin nucleation-promoting factor a.
   
 0.973
pard6b
Par-6 partitioning defective 6 homolog beta (C. elegans).
    
 0.973
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
Server load: low (16%) [HD]