Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
zgc:92287Zgc:92287. (285 aa)    
Predicted Functional Partners:
efcab7
EF-hand calcium-binding domain 7.
    
 0.618
iqce
IQ motif-containing E.
    
 0.613
map3k10
Mitogen-activated protein kinase kinase kinase.
    
 0.582
cdk11b
Cyclin-dependent kinase 11B.
    
 
 0.582
Q1L957_DANRE
Si:dkey-211g8.4.
    
 
 0.564
smpd4
Sphingomyelin phosphodiesterase 4; Catalyzes the hydrolysis of membrane sphingomyelin to form phosphorylcholine and ceramide.
      
 0.562
myl12.1
Myosin, light chain 12, genome duplicate 1.
   
 
 0.528
ccndbp1
Cyclin-D1-binding protein 1 homolog; May negatively regulate cell cycle progression. Belongs to the CCNDBP1 family.
    
 0.518
nup153
Nucleoporin 153.
    
 
 0.514
dlg5a
Discs, large homolog 5a (Drosophila); Belongs to the MAGUK family.
    
 0.509
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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