Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
rgs16Regulator of G protein-signaling 16. (209 aa)    
Predicted Functional Partners:
gnai2a
Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2, like.
  
 
 0.670
gnao1a
Guanine nucleotide-binding protein (G protein), alpha-activating activity polypeptide O, a.
  
 
 0.670
gnat2
Guanine nucleotide-binding protein (G protein), alpha transducing activity polypeptide 2.
  
 
 0.636
gnao1b
Guanine nucleotide-binding protein (G protein), alpha-activating activity polypeptide O, b.
  
 
 0.612
gnai1
Guanine nucleotide-binding protein (G protein), alpha-inhibiting activity polypeptide 1.
    
 0.604
gnai3
Guanine nucleotide-binding protein (G protein), alpha-inhibiting activity polypeptide 3.
    
 0.604
gnav1
Guanine nucleotide-binding protein (G protein) alpha v1.
    
 0.604
gnaia
Guanine nucleotide-binding protein (G protein), alpha-inhibiting activity polypeptide a.
    
 0.604
gnai2b
Guanine nucleotide-binding protein (G protein), alpha-inhibiting activity polypeptide 2b.
    
 0.604
cdk5r2b
Cyclin-dependent kinase 5 activator.
      
 0.600
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
Server load: low (24%) [HD]