Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
zgc:101562Zgc:101562. (246 aa)    
Predicted Functional Partners:
spry1
Sprouty homolog 1, antagonist of FGF-signaling (Drosophila).
    
   0.728
tmbim4
Transmembrane BAX inhibitor motif-containing 4; Belongs to the BI1 family.
      
 0.696
znf516
Zinc finger protein 516.
    
 0.621
acbd6
Acyl-CoA-binding domain-containing protein 6; Binds long-chain acyl-coenzyme A molecules with a strong preference for unsaturated C18:1-CoA. Does not bind fatty acids (By similarity).
      
 0.599
Nox4
NADPH oxidase 4.
      
 0.595
kcnh8
Potassium voltage-gated channel, subfamily H (eag-related), member 8.
      
 0.594
E9QCT1_DANRE
Ig-like domain-containing protein.
      
 0.546
trim13
Tripartite motif-containing 13; E3 ubiquitin ligase involved in the retrotranslocation and turnover of membrane and secretory proteins from the ER through a set of processes named ER-associated degradation (ERAD). This process acts on misfolded proteins as well as in the regulated degradation of correctly folded proteins (By similarity).
    
  0.511
lemd3
LEM domain-containing 3.
    
 
 0.492
ENSDARP00000143124
Uncharacterized protein.
  
  
 
0.467
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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