Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
syncripSynaptotagmin-binding, cytoplasmic RNA-interacting protein. (630 aa)    
Predicted Functional Partners:
igf2bp1
Insulin-like growth factor 2 mRNA-binding protein 1; RNA-binding factor that recruits target transcripts to cytoplasmic protein-RNA complexes (mRNPs). This transcript 'caging' into mRNPs allows mRNA transport and transient storage. It also modulates the rate and location at which target transcripts encounter the translational apparatus and shields them from endonuclease attacks or microRNA-mediated degradation. Plays a direct role in the transport and translation of transcripts required for axonal regeneration in adult sensory neurons (By similarity). Regulates localized beta- actin/AC [...]
   
 0.945
eprs1
Glutamyl-prolyl-tRNA synthetase.
   
 
 0.857
ilf2
Interleukin enhancer-binding factor 2 homolog; Appears to function predominantly as a heterodimeric complex with ILF3. This complex may function to regulate transcription of undefined genes (By similarity).
   
 
 0.851
hnrnpk
Heterogeneous nuclear ribonucleoprotein K.
   
 
 0.821
khdrbs1a
KH domain-containing, RNA-binding, signal transduction-associated 1a.
   
 
 0.811
ilf3b
Interleukin enhancer-binding factor 3 homolog; RNA-binding protein that plays an essential role in the biogenesis of circular RNAs (circRNAs) which are produced by back- splicing circularization of pre-mRNAs. Within the nucleus, promotes circRNAs processing by stabilizing the regulatory elements residing in the flanking introns of the circularized exons. Plays thereby a role in the back-splicing of a subset of circRNAs. As a consequence, participates in a wide range of transcriptional and post- transcriptional processes. Binds to poly-U elements and AU-rich elements (AREs) in the 3'-UT [...]
   
 
 0.809
hnrnpub
Heterogeneous nuclear ribonucleoprotein Ub.
   
 
 0.803
zgc:55733
Zgc:55733.
   
 0.787
hnrnpc
Heterogeneous nuclear ribonucleoprotein C.
   
 0.778
dhx9
DEAH (Asp-Glu-Ala-His) box helicase 9.
   
 
 0.778
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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