Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
nenfNeudesin neurotrophic factor; Belongs to the cytochrome b5 family. (188 aa)    
Predicted Functional Partners:
pgrmc2
Progesterone receptor membrane component 2; Belongs to the cytochrome b5 family.
   
 
0.815
selenom
Selenoprotein M; May function as a thiol-disulfide oxidoreductase that participates in disulfide bond formation; Belongs to the selenoprotein M/F family.
   
   0.762
tent2
Poly(A) RNA polymerase GLD2; Cytoplasmic poly(A) RNA polymerase that adds successive AMP monomers to the 3'-end of specific RNAs, forming a poly(A) tail. In contrast to the canonical nuclear poly(A) RNA polymerase, it only adds poly(A) to selected cytoplasmic mRNAs. May not play a role in replication-dependent histone mRNA degradation (By similarity). Belongs to the DNA polymerase type-B-like family. GLD2 subfamily.
   
 
  0.738
foxred2
FAD-dependent oxidoreductase domain-containing protein 2; Probable flavoprotein which may function in endoplasmic reticulum associated degradation (ERAD). May bind non-native proteins in the endoplasmic reticulum and target them to the ubiquitination machinery for subsequent degradation (By similarity); Belongs to the FOXRED2 family.
   
 
 0.703
pacc1
Proton-activated chloride channel; Proton-activated chloride channel that mediates import of chloride ion in response to extracellular acidic pH. Displays channel activity with distinct kinetic properties compared to the human ortholog channel.
      
 0.700
znhit2
Zinc finger, HIT-type-containing 2.
      
 0.699
poglut1
Protein O-glucosyltransferase 1.
      
 0.698
PAQR9
Progestin and adipoQ receptor family member 9.
   
 
 0.674
sumf2
Sulfatase-modifying factor 2.
      
 0.638
znf622
Zinc finger protein 622.
      
 0.629
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.