STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nenfNeudesin neurotrophic factor; Belongs to the cytochrome b5 family. (188 aa)    
Predicted Functional Partners:
pacc1
Proton-activated chloride channel; Proton-activated chloride channel that mediates import of chloride ion in response to extracellular acidic pH. Displays channel activity with distinct kinetic properties compared to the human ortholog channel.
   
  
 0.588
foxred2
FAD-dependent oxidoreductase domain-containing protein 2; Probable flavoprotein which may function in endoplasmic reticulum associated degradation (ERAD). May bind non-native proteins in the endoplasmic reticulum and target them to the ubiquitination machinery for subsequent degradation (By similarity); Belongs to the FOXRED2 family.
    
 
 0.573
fopnl
Fgfr1op N-terminal-like.
   
    0.549
cyb5a
Cytochrome b5 type A (microsomal); Belongs to the cytochrome b5 family.
   
  
 0.501
cyb5b
Cytochrome b5 type B; Belongs to the cytochrome b5 family.
   
  
 0.498
znf622
Zinc finger protein 622.
   
  
 0.475
znhit2
Zinc finger, HIT-type-containing 2.
      
 0.473
poglut1
Protein O-glucosyltransferase 1.
   
  
 0.466
cox6a1
Cytochrome c oxidase subunit 6A, mitochondrial.
   
  
 0.439
cnpy3
Protein canopy homolog 3; Toll-like receptor (TLR)-specific co-chaperone for HSP90B1. Required for proper TLR folding and hence controls TLR exit from the endoplasmic reticulum. Consequently, required for immune responses (By similarity).
      
 0.439
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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