Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
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[Homology]
Score
scrt1bScratch family zinc finger 1b. (279 aa)    
Predicted Functional Partners:
barhl1a
BarH-class homeodomain transcription factor 3.
   
 
 0.678
pdzrn3b
E3 ubiquitin-protein ligase PDZRN3-B; E3 ubiquitin-protein ligase.
      
 0.571
calm1b
Calmodulin 1b.
   
  
 0.552
camk2n1a
Calcium/calmodulin-dependent protein kinase II inhibitor 1a.
   
  
 0.520
tlx2
T cell leukemia homeobox 2.
   
 
 0.501
lbx2
Ladybird homeobox homolog 2 (Drosophila).
      
 0.465
atoh8
Protein atonal homolog 8; Transcription factor that binds a palindromic (canonical) core consensus DNA sequence 5'-CANNTG- 3' known as an E-box element, possibly as a heterodimer with other bHLH proteins (By similarity). During development, is required for heart looping and swim bladder formation by acting in concert with GATA4 AND ZFPM1. During the development of both the retina and skeletal muscles is required for neural retinal cell through modulating PAX6 and NEUROG3 expression and myogenic differentiation.
      
 0.463
nhlh2
Nescient helix loop helix 2.
   
 
 0.461
sox12
Transcription factor SOX.
   
  
 0.453
uncx
Homeobox protein unc-4 homolog.
   
  
 0.431
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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