Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
kpnb3Karyopherin (importin) beta 3. (1093 aa)    
Predicted Functional Partners:
kpnb1
Karyopherin (importin) beta 1.
   
 0.999
ipo4
Importin 4.
   
 0.995
ipo7
Importin 7.
   
 0.990
ipo8
Importin 8.
   
 0.990
ipo9
Importin 9.
   
 0.982
ipo11
Importin 11.
   
 
 0.975
tnpo3
Transportin 3.
   
 
 0.970
cse1l
Exportin-2; Export receptor for importin alpha. Mediates importin-alpha re-export from the nucleus to the cytoplasm after import substrates have been released into the nucleoplasm (By similarity). Negatively regulates fluid secretion and plays a role in fluid homeostasis by downregulating cftr activity.
   
 
 0.962
tnpo1
Transportin 1.
   
 0.942
tnpo2
Transportin 2 (Importin 3, Karyopherin beta 2b).
   
 0.942
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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