Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
ephx2Epoxide hydrolase 2, cytoplasmic. (557 aa)    
Predicted Functional Partners:
ephx4
Epoxide hydrolase 4.
 
 
0.941
ephx5
Epoxide hydrolase 5.
  
 
 0.922
ephx1
Epoxide hydrolase; Biotransformation enzyme that catalyzes the hydrolysis of arene and aliphatic epoxides to less reactive and more water soluble dihydrodiols by the trans addition of water. Belongs to the peptidase S33 family.
  
 
0.911
cyp1a
Cytochrome P450, family 1, subfamily A; Belongs to the cytochrome P450 family.
   
 0.902
E7F661_DANRE
Si:ch73-389b16.2.
  
 
 0.893
ENSDARP00000137689
EHN domain-containing protein.
  
 
 0.877
cyp4f3
Cytochrome P450, family 4, subfamily F, polypeptide 3; Belongs to the cytochrome P450 family.
   
 0.874
cyp4t8
Cytochrome P450, family 4, subfamily T, polypeptide 8.
   
 0.874
cyp1d1
Cytochrome P450, family 1, subfamily D, polypeptide 1; Belongs to the cytochrome P450 family.
   
 0.869
cyp1b1
Cytochrome P450, family 1, subfamily B, polypeptide 1; Belongs to the cytochrome P450 family.
   
 0.869
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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