STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ywhablTyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide-like; Belongs to the 14-3-3 family. (245 aa)    
Predicted Functional Partners:
cdc25b
Cell division cycle 25B.
   
 0.953
tgm1l1
Transglutaminase 1-like 1.
   
  
 0.571
tgm1l4
Transglutaminase 1-like 4.
   
  
 0.571
pi4kb
Phosphatidylinositol 4-kinase beta; Phosphorylates phosphatidylinositol (PI) in the first committed step in the production of the second messenger inositol- 1,4,5,-trisphosphate (PIP).
    
 
 0.569
tgm1l3
Transglutaminase 1-like 3.
   
  
 0.562
actb1
Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA.
  
 
 0.543
mitfb
Microphthalmia-associated transcription factor b.
    
 
 0.528
stk11
Serine/threonine kinase 11; Belongs to the protein kinase superfamily.
   
 
 0.522
cdc25d
Cell division cycle 25 homolog d.
    
 
 0.513
tgm1
Transglutaminase 1, K polypeptide.
   
  
 0.481
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.