Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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sec61bProtein transport protein Sec61 subunit beta; Necessary for protein translocation in the endoplasmic reticulum. (97 aa)    
Predicted Functional Partners:
sec61a1
Protein transport protein Sec61 subunit alpha-like 1; Appears to play a crucial role in the insertion of secretory and membrane polypeptides into the ER. It is required for assembly of membrane and secretory proteins. Found to be tightly associated with membrane-bound ribosomes, either directly or through adapter proteins (By similarity). Plays a role in the pronephric kidney tubule development.
   
 0.999
sec61a1l
Protein transport protein Sec61 subunit alpha-like 2; Appears to play a crucial role in the insertion of secretory and membrane polypeptides into the ER. It is required for assembly of membrane and secretory proteins. Found to be tightly associated with membrane-bound ribosomes, either directly or through adaptor proteins (By similarity).
   
 0.999
sec61g
SEC61 translocon gamma subunit.
   
 0.999
sec63
SEC63 homolog, protein translocation regulator.
   
 
 0.996
ssr3
Signal sequence receptor, gamma.
   
 
 0.996
ssr4
Signal sequence receptor, delta.
   
 
 0.996
arl6ip1
ADP-ribosylation factor-like 6-interacting protein 1.
   
 0.987
ssr2
Translocon-associated protein subunit beta; TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins.
   
 
 0.987
rpl21
Ribosomal protein L21.
   
 
 0.978
rps4x
40S ribosomal protein S4, X isoform; Belongs to the eukaryotic ribosomal protein eS4 family.
   
 
 0.978
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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