Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
prtgbProtogenin B; May play a role in anteroposterior axis elongation. Belongs to the immunoglobulin superfamily. DCC family. (968 aa)    
Predicted Functional Partners:
capslb
Calcyphosine-like b.
    
 
 0.730
LOC108179070
Protogenin A; May play a role in anteroposterior axis elongation. Belongs to the immunoglobulin superfamily. DCC family.
 
     
0.713
arpp19b
cAMP-regulated phosphoprotein 19b; Protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A (PP2A) during mitosis. Belongs to the endosulfine family.
      
 0.705
cradd
CASP2 and RIPK1 domain-containing adaptor with death domain.
      
 0.662
fam214a
Protein FAM214A.
      
 0.662
ensab
Endosulfine alpha b; Protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A (PP2A) during mitosis. Belongs to the endosulfine family.
      
 0.662
rsl24d1
Probable ribosome biogenesis protein RLP24; Involved in the biogenesis of the 60S ribosomal subunit. Ensures the docking of GTPBP4/NOG1 to pre-60S particles (By similarity).
 
    
 0.650
nectin1a
Nectin cell adhesion molecule 1a.
    
 0.630
atp8b2
Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
      
 0.588
wfikkn2b
WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain-containing 2b.
    
 
 0.547
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.