Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
wdfy2WD repeat and FYVE domain-containing 2. (400 aa)    
Predicted Functional Partners:
cdc123
Cell division cycle protein 123 homolog; Required for S phase entry of the cell cycle; Belongs to the CDC123 family.
   
 
 0.841
cenpn
Centromere protein N.
      
 0.792
cdc16
Cell division cycle 16 homolog (S. cerevisiae).
   
 0.774
pard6gb
Par-6 partitioning defective 6-like protein gamma.
      
 0.733
slc17a5
Solute carrier family 17 member 5.
   
  
 0.728
supt7l
Suppressor of Ty 7 (S. cerevisiae)-like.
    
 
 0.689
atp5mc1
ATP synthase membrane subunit c locus 1; Belongs to the ATPase C chain family.
      
 0.683
cldn15a
Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.
      
 0.682
nudcd1
NudC domain-containing protein 1.
    
   0.612
wdfy4
WDFY family member 4.
      
 0.612
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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