STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
wdfy2WD repeat and FYVE domain-containing 2. (400 aa)    
Predicted Functional Partners:
cdc123
Cell division cycle protein 123 homolog; Required for S phase entry of the cell cycle; Belongs to the CDC123 family.
   
  
 0.906
slc17a5
Solute carrier family 17 member 5.
   
  
 0.875
cdc16
Cell division cycle 16 homolog (S. cerevisiae).
   
 
 0.864
cenpn
Centromere protein N.
   
  
 0.836
cldn15a
Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.
      
 0.823
atp5mc1
ATP synthase membrane subunit c locus 1; Belongs to the ATPase C chain family.
     
 0.810
pard6gb
Par-6 partitioning defective 6-like protein gamma.
      
 0.806
supt7l
Suppressor of Ty 7 (S. cerevisiae)-like.
    
 
 0.774
wdfy4
WDFY family member 4.
   
  
 0.703
taf2
Transcription initiation factor TFIID subunit 2; Transcription factor TFIID is one of the general factors required for accurate and regulated initiation by RNA polymerase II. TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors. It requires core promoter-specific cofactors for productive transcription stimulation. TAF2 stabilizes TFIID binding to core promoter (By similarity).
   
 
 0.699
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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