STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
enpp6Glycerophosphocholine cholinephosphodiesterase ENPP6; Choline-specific glycerophosphodiesterase that hydrolyzes glycerophosphocholine (GPC) and lysophosphatidylcholine (LPC) and contributes to supplying choline to the cells. Has a preference for LPC with short (12:0 and 14:0) or polyunsaturated (18:2 and 20:4) fatty acids. In vitro, hydrolyzes only choline-containing lysophospholipids, such as sphingosylphosphorylcholine (SPC), platelet-activating factor (PAF) and lysoPAF, but not other lysophospholipids. Belongs to the nucleotide pyrophosphatase/phosphodiesterase family. (459 aa)    
Predicted Functional Partners:
lpcat4
Lysophosphatidylcholine acyltransferase 4.
   
 
 0.930
enpp2
Ectonucleotide pyrophosphatase/phosphodiesterase 2.
  
  
0.922
gdpd3b
Glycerophosphodiester phosphodiesterase domain-containing 3b.
  
 
 0.910
gdpd1
Glycerophosphodiester phosphodiesterase domain-containing 1.
  
 
 0.910
gdpd3a
Glycerophosphodiester phosphodiesterase domain-containing 3a.
  
 
 0.910
pla2g12b
Phospholipase A2, group XIIB.
   
 
 0.908
tmem86b
Transmembrane protein 86B.
   
 
 0.907
E7EXS7_DANRE
Si:dkey-177p2.18.
     
 0.905
K7DYE2_DANRE
Si:ch211-214p16.3.
     
 0.905
zgc:92162
Phospholipase A(2).
     
 0.905
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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