Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
mxd4MAX dimerization protein 4. (207 aa)    
Predicted Functional Partners:
max
Protein max; Transcription regulator. Forms a sequence-specific DNA- binding protein complex with MYC or MAD which recognizes the core sequence 5'-CAC[GA]TG-3'. The MYC-MAX complex is a transcriptional activator, whereas the MAD-MAX complex is a repressor (By similarity).
    
 
 0.971
mlx
MAX dimerization protein MLX.
    
 
 0.869
zgc:123105
Putative monooxygenase p33MONOX; Potential NADPH-dependent oxidoreductase.
      
 0.782
ngrn
Neugrin, neurite outgrowth-associated.
      
 0.702
LOC100333406
GLIS family zinc finger 1b.
    
 0.698
znf410
Zinc finger protein 410.
    
 0.673
caly
Calcyon neuron-specific vesicular protein.
      
 0.669
creb1b
cAMP-responsive element-binding protein 1b.
      
 0.662
mlxip
MLX-interacting protein.
      
 0.638
sh3bgrl2
SH3 domain-binding glutamic acid-rich-like protein 2.
      
 0.637
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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