Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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experimentally determined
co-expression
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gene co-occurrence
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[Homology]
Score
bckdha2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). (446 aa)    
Predicted Functional Partners:
pdhb
Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
 0.999
dbt
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.
 
 0.999
bckdhb
Branched chain keto acid dehydrogenase E1 subunit beta.
 0.999
dldh
Dihydrolipoyl dehydrogenase.
  
 
 0.996
bcat2
Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
  
 
 0.983
pdhx
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.
 
 0.975
bcat1
Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
  
 
 0.974
dlat
Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
 
 0.965
ldhba
L-lactate dehydrogenase B-A chain; Belongs to the LDH/MDH superfamily. LDH family.
   
 
 0.958
ldha
L-lactate dehydrogenase A chain; Belongs to the LDH/MDH superfamily. LDH family.
   
 
 0.958
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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