Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
wipi1WD repeat domain, phosphoinositide-interacting 1. (453 aa)    
Predicted Functional Partners:
atg16l1
ATG16 autophagy-related 16-like 1 (S. cerevisiae).
   
 0.994
ATG2A
Si:ch73-45o6.2.
    
 0.992
atg2b
Autophagy-related 2B.
    
 0.989
atg16l2-2
ATG16 autophagy-related 16-like 2 (S. cerevisiae).
   
 0.983
atg16l2
ATG16 autophagy-related 16-like 2 (S. cerevisiae).
   
 0.975
atg5
Autophagy protein 5; Involved in autophagic vesicle formation.
    
 
 0.967
atg9b
Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family.
   
 0.965
atg12
Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.
    
 
 0.961
wipi2
WD repeat domain, phosphoinositide-interacting 2.
     
  0.944
wdr45b
WD repeat domain phosphoinositide-interacting protein 3; Component of the autophagy machinery that controls the major intracellular degradation process by which cytoplasmic materials are packaged into autophagosomes and delivered to lysosomes for degradation. In the cellular response to starvation, may also function in the inhibition of the mTORC1 signaling pathway. Belongs to the WD repeat SVP1 family.
   
0.927
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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