Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene co-occurrence
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[Homology]
Score
nifkMKI67 FHA domain-interacting nucleolar phosphoprotein; Plays an essential role in early embryonic development. (269 aa)    
Predicted Functional Partners:
rsl1d1
Ribosomal L1 domain-containing 1.
   
 
 0.999
rrs1
Ribosome biogenesis regulatory protein; Involved in ribosomal large subunit assembly. Belongs to the RRS1 family.
   
 
 0.998
rpf2
Ribosome production factor 2 homolog.
   
 
 0.997
rbm28
RNA-binding motif protein 28.
   
 
 0.995
mak16
Protein MAK16 homolog; Plays an essential role in early embryonic development.
   
 
 0.995
nop58
NOP58 ribonucleoprotein homolog (yeast).
   
 
 0.995
gtpbp4
Nucleolar GTP-binding protein 1; Involved in the biogenesis of the 60S ribosomal subunit. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. NOG subfamily.
   
 
 0.994
nip7
60S ribosome subunit biogenesis protein NIP7 homolog; Required for proper 34S pre-rRNA processing and 60S ribosome subunit assembly.
   
 
 0.994
noc2l
NOC2-like nucleolar-associated transcriptional repressor.
   
 
 0.994
nop2
NOP2 nucleolar protein homolog (yeast); Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
   
 
 0.994
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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