Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
nitr7bNovel immune-type receptor 7b, allele 2. (243 aa)    
Predicted Functional Partners:
nitr1i
Novel immune-type receptor 1i.
   
  
 0.902
nitr2b
Novel immune-type receptor 2b, allele 1.
   
  
 0.888
nitr3a
Novel immune-type receptor 3c.
     
 0.884
nitr4a
Novel immune-type receptor 4a.
   
  
 0.884
nitr9
Novel immune-type receptor 9.
      
 0.786
lta
Lymphotoxin alpha (TNF superfamily, member 1); Belongs to the tumor necrosis factor family.
   
  
 0.704
plcd3a
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3-A; Hydrolyzes the phosphatidylinositol 4,5-bisphosphate (PIP2) to generate 2 second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). DAG mediates the activation of protein kinase C (PKC), while IP3 releases Ca(2+) from intracellular stores (By similarity).
      
 0.680
nitr6b
Novel immune-type receptor 6b.
   
  
 0.669
nkl.1
NK-lysin tandem duplicate 2.
      
 0.662
nitr6b-2
Novel immune-type receptor 6b.
      
 0.661
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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